^ Jump up to: a b Rolfe, HM (December 2014). “A review of nicotinamide: treatment of skin diseases and potential side effects”. Journal of Cosmetic Dermatology (Review). 13 (4): 324–8. doi:10.1111/jocd.12119. PMID 25399625.
Each month I would try my best to avoid ending up in a heap on the floor of the lab. I would the one room with a chair where I could lie all the way back and put my feet up. I’d take slow, deep breaths until the nurse removed the needle, wait a few more minutes for good measure before sitting up, and then barring any lightheadedness, I’d breathe a sigh of relief that I wouldn’t be back in the chair for another 30 days. Still, on more than one occasion I wouldn’t make it further than the waiting room before I’d slump down into a chair, putting head between my knees until the dizziness would pass.
Avoid using strong soaps or products that strip all oil and moisture from your skin. Your skin’s natural reaction is to try to compensate by producing more oil, which will worsen your acne in the long run!
They may also refer you to a dermatologist for assessment and possible prescription of isotretinoin. After a course of isotretinoin, most people are cured of their acne. Isotretinoin can have side-effects that need to be carefully explained to you before commencing treatment.
Different variants of acne exist, including acne conglobata, acne fulminans, acne mechanica, excoriated acne, chloracne, drug-induced acne (e.g., from anabolic steroids, corticosteroids, isoniazid, lithium, phenytoin), neonatal and infantile acne, and occupational acne. These variations have a similar clinical and histologic appearance to acne vulgaris, but they are distinguishable by clinical setting, severity and associated symptoms. The common differential diagnosis of acne includes folliculitis, keratosis pilaris, perioral dermatitis, seborrheic dermatitis and rosacea.
Topical (external) applications: Antibacterial cleansers come in the form of gels, creams, and lotions that are applied to the affected area. The active ingredients that kill surface bacteria include benzoyl peroxide, sulfur, and resorcinol. Some brands promoted on the Internet and cable TV (such as ProActiv) are much more costly than identical and sometimes more potent products one can buy in the drugstore.
Polycystic Ovary Syndrome (PCOS) is the result of significant shifts in a woman’s hormones. This shift can cause the production of androgens to increase and overwhelm estrogen levels, signaling the production of excess sebum. This hormonal imbalance can result in painful cysts, period changes, infertility issues, heart disease, diabetes, and skin conditions like acne. One research study performed purported that 27 percent of all women struggling with acne also were diagnosed with PCOS. Those with PCOS are more prone to inflammation, which can worsen the severity of acne.
Oral isotretinoin is very effective. But because of its potential side effects, doctors need to closely monitor anyone they treat with this drug. Potential side effects include ulcerative colitis, an increased risk of depression and suicide, and severe birth defects. In fact, isotretinoin carries such serious risk of side effects that all people receiving isotretinoin must participate in a Food and Drug Administration-approved risk management program.
Disclosure: Received consulting fee from Valeant for consulting; Received grant/research funds from Medicis for other; Received consulting fee from Galderma for consulting; Received consulting fee from Promius for consulting; Received consulting fee from Pharmaderm for consulting; Received consulting fee from Onset for consulting.
Tea tree oil, from the Melaleuca alternifolia tree, has anti-bacterial properties when applied topically to skin. One study showed that 5% tea tree oil was as effective as 5% benzoyl peroxide topically for reducing the number of inflamed acne lesions. Unfortunately, some people experience burning, stinging and redness when they use it. One warning – only use it topically, never by mouth.
Frankincense oil reduces the inflammation and also kills the bacteria. It tones the skin and promotes the growth of healthy cells (7). Use this essential oil to get rid of that stubborn pimple on your forehead.
Among the most popular OTC remedies is salicylic acid, which is incorporated into gels, wipes, creams, and sprays. The acid reduces swelling and redness and unplugs pores. To keep skin from becoming too dry, look for formulas geared to adult women, not teens (aim for 2% salicylic acid to start). Some skin care lines offer salicylic acid products that address acne and wrinkles alike. Murad Acne & Wrinkle Reducer ($44; ulta.com) uses the acid to clean skin and throws in a kombucha extract to stimulate collagen production.
Combination therapy—using medications of different classes together, each with a different mechanism of action—has been demonstrated to be a more efficacious approach to acne treatment than monotherapy. The use of topical benzoyl peroxide and antibiotics together has been shown to be more effective than antibiotics alone. Similarly, using a topical retinoid with an antibiotic clears acne lesions faster than the use of antibiotics alone. Frequently used combinations include the following: antibiotic and benzoyl peroxide, antibiotic and topical retinoid, or topical retinoid and benzoyl peroxide. The pairing of benzoyl peroxide with a retinoid is preferred over the combination of a topical antibiotic with a retinoid since both regimens are effective but benzoyl peroxide does not lead to antibiotic resistance.