Oral isotretinoin is the best oral retinoid treatment for severe acne. It reduce* sebum (oil) secretion, acnes infection as well as has anti-inflammatory properties. It is used for patient that does not respond to regular treatment of severe acne.
Treatment is normally no different than that for the milder acne forms. Over-the-counter products and even some home remedies can be effective, but since this type is relatively severe, it may be necessary to visit a dermatologist if the products or home remedies you are using are not effective. Many, though not all, over-the-counter products contain three important agents used in fighting acne:
Topical retinoids are comedolytic and anti-inflammatory. They normalize follicular hyperproliferation and hyperkeratinization. Topical retinoids reduce the numbers of microcomedones, comedones, and inflammatory lesions.  Topical retinoids should be initiated as first-line therapy for both comedonal and inflammatory acne lesions and continued as maintenance therapy to inhibit further microcomedone formation. 
^ Jump up to: a b Foti, C; Romita, P; Borghi, A; Angelini, G; Bonamonte, D; Corazza, M (September 2015). “Contact dermatitis to topical acne drugs: a review of the literature”. Dermatologic Therapy (Review). 28 (5): 323–9. doi:10.1111/dth.12282. PMID 26302055.
Each inflamed spot will heal eventually. In some cases, the area of skin that was inflamed remains discoloured for several months after the inflammation has gone (post-inflammatory hyperpigmentation). This is often more noticeable in darker-skinned people. Also, a small pitted scar is commonly left on the skin where there was an inflamed spot. These small scars often do not fade fully and are a marker in older people that they once had inflamed acne spots.
Several scales exist to grade the severity of acne vulgaris, but no single technique has been universally accepted as the diagnostic standard. Cook’s acne grading scale uses photographs to grade severity from 0 to 8 (0 being the least severe and 8 being the most severe). This scale was the first to use a standardized photographic protocol to assess acne severity; since its creation in 1979, the scale has undergone several revisions. The Leeds acne grading technique counts acne lesions on the face, back, and chest and categorizes them as inflammatory or non-inflammatory. Leeds scores range from 0 (least severe) to 10 (most severe) though modified scales have a maximum score of 12. The Pillsbury acne grading scale simply classifies the severity of the acne from 1 (least severe) to 4 (most severe).
Accutane provides long-term remission of acne symptoms in about 2/3 of people who take an adequate dosage (1mg/kg). However, the power and permanency of the drug, along with its ability to cause severe birth defects and other side effects, necessitate a serious decision making and planning process with a trusted doctor, family, and caring friends.
Some topical acne treatments (described below) may dry the skin. If this occurs, use a fragrance-free, water-based moisturising cream. Do not use ointments or oil-rich creams, as these may clog the holes of the skin (pores).
^ Jump up to: a b c d Sagransky, M; Yentzer, BA; Feldman, SR (October 2009). “Benzoyl peroxide: A review of its current use in the treatment of acne vulgaris”. Expert Opinion on Pharmacotherapy (Review). 10 (15): 2555–62. doi:10.1517/14656560903277228. PMID 19761357.
Folliculitis: Pimples can occur on other parts of the body, such as the abdomen, buttocks, or legs. These represent not acne but inflamed follicles. If these don’t go away on their own, doctors can prescribe oral or external antibiotics, generally not the same ones used for acne.
omg yall are doing it all wrong XD my names jasmine and also to get rid of people try toothpaste mixed with lemons and honey its weird but also mix in some clearasil it really orks for me yall should try it somtimes also use ice it makes it better ;D
Doctors advise treating pimples immediately to prevent them from spreading. Acne, if left untreated, can leave scars on the skin, which become very difficult to remove. Pimples can develop due to various reasons. Here are a few:
Rolling scars basically look like waves. They’re also referred to as rolling hill acne scars sometimes because they can look like tiny hills on top of your skin. These tend to be shallow, but they appear more grouped together.
Boost your lemon juice by adding turmeric into the mix. “Turmeric contains antioxidants and anti-inflammatory properties that help acne lesions resolve quicker and scars to fade faster,” says Dr. Goldenberg.
2. Turn up the heat. When you have painful, cystic pimples beneath the surface of your skin that haven’t come to a head, use heated compresses to draw the infection to the surface. Encouraging your body to sweat — whether in a sauna, steam room or in an exercise class or at the gym — is a great way to help your body rid the skin of toxins and bacteria.
Dermalogica sells its full-size Clear Start products a la carte (all at around $20 — this line is definitely not made for the thrifty), and there are even more options than the five in the travel kit. We were surprised how much the products appealed to us: We didn’t pay attention to the aesthetics of most acne treatments, but the Clear Start caught our eye in a god way. More importantly, we loved the mix of salicylic acid and benzoyl peroxide, plus all-natural heavy hitters like tea tree oil and witch hazel. And in addition to the wash, toner, moisturizer, and treatments, the kit includes an acne-safe (read: oil-free) sunscreen in its lineup.
April W. Armstrong, MD, MPH, is an assistant professor of dermatology at the University of California Davis Health System. She tells patients to give a product 1 month and then keep using it if they notice any improvement.
I have had acne on my butt for quite some time. I’ve tried several other products and noting has worked. Dermalmd acne serum worked after about a week of application and as long as I keep using it, things are great.
Castor oil cleanses the skin and pulls out all the dirt, impurities, and even the bacteria (19). The ricinoleic acid present in it conditions the skin and makes it softer and healthier (20). Cystic acne can also be effectively treated with this oil.
I have often heard PCOS referred to as the “Thief of Womanhood.” If left unmanaged, it can rob you of your fertility, femininity, health and happiness. I understand this label and struggled with all of the PCOS symptoms. It wasn’t until I realized that a PCOS diagnosis isn’t the end of the world – it is a chance for a new beginning – that my real healing journey began. When I started taking care of myself, loving myself and making me a priority (in spite of my PCOS) I became a new woman. My husband started calling me a diva. What a compliment!
The Journal of Clinical and Aesthetic Dermatology states that salicylic acid and benzoyl peroxide are by far the most common acne ingredients and they’re effective in double-blind studies of patients with mild-to-moderately severe acne. We looked for kits that included at least one ingredient targeting each camp: the comedones and the pimples.
^ Jump up to: a b c d Vallerand, I.A.; Lewinson, R.T.; Farris, M.S.; Sibley, C.D.; Ramien, M.L.; Bulloch, A.G.M.; Patten, S.B. (2018-01-01). “Efficacy and adverse events of oral isotretinoin for acne: a systematic review”. British Journal of Dermatology. 178 (1): 76–85. doi:10.1111/bjd.15668. ISSN 1365-2133.
“Some teenagers are very confident and self-assured even if their face looks terrible, so they’re easy to deal with,” Taylor said. “But then there are kids who become very depressed and withdrawn and may isolate themselves. With them I try to be hopeful and optimistic, upbeat and positive, to tell them that I know it’s hard having this condition and to show some sympathy. Or empathy, really, because I had acne, too, when I was a teen.”
Immediately after cleansing, apply a topical acne treatment. Dr. Bowe suggests Aczone, a prescription anti-inflammatory and antibacterial gel. Unlike benzoyl peroxide, which can be drying, Aczone contains dapsone, a gentle yet effective ingredient that is ideal for adult female skin.
While we should remain open to holistic and home remedies, and hopefully someday get to the root of acne, at the current time there do not appear to be any holistic or home remedies that provide consistent clearing across the population.