Some sebum may collect under blocked pores. You can see this as small spots called pimples or papules. In some cases, acne does not progress beyond this mild-to-moderate stage when you can see a number of small pimples, blackheads and whiteheads.
^ Jump up to: a b c d e Walsh, TR; Efthimiou, J; Dréno, B (March 2016). “Systematic review of antibiotic resistance in acne: an increasing topical and oral threat”. Lancet Infectious Diseases (Systematic Review). 16 (3): e23–33. doi:10.1016/S1473-3099(15)00527-7. PMID 26852728.
Pharaohs are recorded as having had acne, which may be the earliest known reference to the disease. Since at least the reign of Cleopatra (69–30 BC), the application of sulfur to the skin has been recognized as a useful treatment for acne. The sixth-century Greek physician Aëtius of Amida is credited with coining the term “ionthos” (ίονθωξ,) or “acnae”, which is believed to have been a reference to facial skin lesions that occur during “the ‘acme’ of life” (puberty).
A few weeks ago, I made a drastic change to my diet to see if it would affect my acne. I replaced all my beverages with water or natural green-tea (no sugar!), I cut out ALL junk food and sugary foods, I went gluten-free and dairy-free, I included more fruits and veggies, and I ate low-glycemic foods. I was also taking zinc supplements, so you should research the effects of zinc for acne if you are looking to try a new remedy. With all of these combined, my [severe, cystic] acne cleared up in 2-3 weeks. Unfortunately, I had to stop because I had exams coming up and could not maintain the strict lifestyle. I truly believe acne can be cured by diet; the over-the-counter products can definitely help to reduce acne, but I do not think it will get rid of it forever. To everyone who is still struggling, including myself for the time being, please give this a try.
Topical retinoids are comedolytic and anti-inflammatory. They normalize follicular hyperproliferation and hyperkeratinization. Topical retinoids reduce the numbers of microcomedones, comedones, and inflammatory lesions.  Topical retinoids should be initiated as first-line therapy for both comedonal and inflammatory acne lesions and continued as maintenance therapy to inhibit further microcomedone formation. 
Neem oil and neem powder are powerful natural treatments for pimples. They have powerful antibacterial properties. You can get them to buy online or at the local organic or natural food store in your area. Rinse your face with warm water to open up the pores of your skin. Use cotton buds to daub the oil and apply it directly to the pimples. You can also mix the powder with a small quantity of water to form a paste and apply it to the spots. Leave the paste on throughout the night so it penetrate the skin destroy all the bacteria in the pimples.
Tea tree oil: this contains antibacterial properties and works well for the treatment of acne. Dab a little onto each pimple and leave for no longer than thirty minutes before rinsing off. Aloe Vera gel is a cooling agent and may be added to the tea tree oil. Leave this on for no longer than twenty minutes before washing off in cool water. If your skin is very sensitive, then avoid using tea tree oil.
This latest development in the acne treatment field is recommended for people who suffer from red, inflamed acne. The bacteria that cause acne, Propionibacterium acnes, is sensitive to blue light. This means that when this bacteria that is residing in the oil glands of your skin is exposed to blue light, it dies. Also, the heat that accompanies the blue light causes the oil glands to shrink and reduces the sebum production. A wholesome treatment for acne!
The microinjury triggers the skin repair process by producing new collagen and elastin in the skin’s dermis, thereby improving the appearance of scars and rejuvenating the skin. This is what we call a collagen induction therapy.
If you plan to spend time outdoors, it is important to know that isotretinoin can make your skin more sensitive to the sun. You can sunburn unexpectedly and quickly. To protect your skin, dermatologists recommend that people taking isotretinoin:
This medication is a diuretic — that is, a “water pill” that causes frequent urination. It also blocks receptors for male hormones, which modulates the hormonal surges that can stimulate oil production, causing acne. Spironolactone isn’t approved by the FDA to treat acne and probably won’t be, Schlosser says, because as a generic drug there’s little motivation for a manufacturer to pay for the trials needed to go through the approval process. But most dermatologists agree that it works well as an acne treatment.
^ Jump up to: a b c d Sagransky, M; Yentzer, BA; Feldman, SR (October 2009). “Benzoyl peroxide: A review of its current use in the treatment of acne vulgaris”. Expert Opinion on Pharmacotherapy (Review). 10 (15): 2555–62. doi:10.1517/14656560903277228. PMID 19761357.
2. African Bantus and Zulus: These original African warriors eat a low glycemic diet with no wheat, no milk and no refined sugar or starches. Their teenagers and young adult do not have acne, if they stick to the original tribal diet.
Never pick out your own antibiotic for acne, even if antibiotics are available without a prescription in the country where you live. It is important to avoid getting a secondary infection that can be much worse than acne.
Unlike oral dapsone which is sometimes prescribed for leprosy and other skin infections, topical dapsone does not come with potentially dangerous blood related side effects.4-5 Side effects of topical dapsone are normally mild in nature and can include dryness, rash, and burning.6
^ Jump up to: a b Beylot, C; Auffret, N; Poli, F; Claudel, JP; Leccia, MT; Del Giudice, P; Dreno, B (March 2014). “Propionibacterium acnes: an update on its role in the pathogenesis of acne”. Journal of the European Academy of Dermatology and Venereology: JEADV (Review). 28 (3): 271–8. doi:10.1111/jdv.12224. PMID 23905540.
Glycolic acid is an alpha hydroxy acid that exfoliates the skin, helping to get rid of the dead skin cells that can clog pores. Just like salicylic acid, you can find glycolic in washes, peels, moisturizers, and serums at your local beauty store or drugstore.
Wear clothing that you enjoy. What you wear affects how you feel and how others perceive you. Choose clothing that flatters you and that you feel beautiful in. Your confidence will shine through. If you are having a breakout and not feeling that great, try dressing up a bit. You may feel better about yourself.